PD-L1 Recombinant Rabbit Monoclonal Antibody

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PD-L1 Recombinant Rabbit Monoclonal Antibody

PD-L1 Recombinant Rabbit Monoclonal Antibody

Recombinant Rabbit Monoclonal Antibody

Programmed cell death ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a type 1 transmembrane protein involved in the regulation of cellular and humoral immune responses. The interaction of PD-L1 with its receptor PD-1 provides both stimulatory and inhibitory signals in regulating T cell activation and tolerance during pregnancy tissue allografts, autoimmune disease and malignant transformation.

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Description
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Description

Specifications

Catalog No.: BX00005

Clone No.: BP6141

Application: IHC-P

Subcellular location: Membrane

Control: Placenta

Recommended method: HIER

Volume: 100μl/vial, 1ml/vial

Dilution: 1:100-1:200

Immunogen: Recombinant full length protein corresponding to Human PD-L1 (extracellular). The immunogen contains the specific extracellular domain of huPD-L1 (F19-T239).

Reference

1.Muenst S1, et al. Breast Cancer Res Treat. 2014 Jul;146(1):15-24.
2.Lim SH, et al. Expert Opin Biol Ther. 2016;16(3):397-406.